| 07/03/2026 | Arsenal | 0 | 0 | Southampton | Drawn |
| 14/03/2026 | Southampton | 1 | 1 | Wigan | Drawn |
| 21/03/2026 | Walsall | Southampton | |||
| 28/03/2026 | Southampton | Gillingham | |||
| 04/04/2026 | Liverpool | Southampton | |||
| 11/04/2026 | Southampton | West Ham | |||
| 18/04/2026 | Southampton | Tottenham | |||
| 25/04/2026 | Man Utd | Southampton | |||
| 02/05/2026 | Southampton | Man City | |||
| 09/05/2026 | Southampton | Arsenal | |||
| 16/05/2026 | Wigan | Southampton | |||
| 23/05/2026 | Southampton | Walsall | |||
| 30/05/2026 | Gillingham | Southampton | |||
| 06/06/2026 | Southampton | Liverpool | |||
| 13/06/2026 | West Ham | Southampton | |||
| 20/06/2026 | Tottenham | Southampton | |||
| 27/06/2026 | Southampton | Man Utd | |||
| 04/07/2026 | Man City | Southampton |